Effects of creatine monohydrate supplementation and exercise on depression-like behaviors and raphe 5-HT neurons in mice

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Effects of creatine monohydrate supplementation and exercise on depression-like behaviors and raphe 5-HT neurons in mice

PURPOSE The effects of creatine and exercise on chronic stress-induced depression are unclear. In the present study, we identified the effects of 4-week supplementation of creatine monohydrate and/or exercise on antidepressant behavior and raphe 5-HT expression in a chronic mild stress-induced depressed mouse model. METHODS Seven-week-old male C57BL/6 mice (n=48) were divided randomly into 5 ...

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ژورنال

عنوان ژورنال: Journal of Exercise Nutrition & Biochemistry

سال: 2016

ISSN: 2233-6834,2233-6842

DOI: 10.20463/jenb.2016.09.20.3.4